Dr. Weeks, in a letter reprinted on the Internet dated 8/1/99 stated "The world's literature is compelling responsible physicians to attend to anti-aging measures for our patients and Biotropin (GH anolog) is the crown jewel in any physician's black bag." Dr. Weeks went on to summarize "This study on oral Biotropin impressed me and being skeptical by nature I find myself surprised at my enthusiasm for this spray product.  The option before us now is to offer the benefits of HGH at an affordable and very effective form for our patients."

     All 44 patients (half were on placebo) were asked to and did not change their normal exercise or eating habits.  Only one person dropped out of the study (the youngest and least likely to benefit).  Patients ranged in age from 41 to 82, male and females responded with significant yet not excessive increased IGF-1 levels to "youthful" levels.  The average percentage change in the 21 patients on the actual oral GH for IGF-1 was over 45% in 60 days.  Those on placebo, thinking they were on the product, yet with no active ingredients showed "no" change in this controlled study.  No one went out of the normal youthful range while using oral GH for IGF-1 levels which speaks to the lack of potential toxicity at the 2 sprays three times a day dosage.  A significant loss of body fat by 11%, with an appreciated increase in lean muscle mass (as measured by the very sensitive bioelectric Tanita method used in Bariatrics clinics).  The overall weight reduction was 4.28% in 60 days as compared to placebo. This shift of weight from fat to muscle (muscle weighs three times more than fat) is further proof that the oral GH spray works and with far less expense.  No one in the study using oral spray reported any adverse side effects.  All this is great news for patients and the oral spray is available without needing a prescription.

Dr. Shortt Reports Oral GH Works   
      Dr. James Shortt MD., Medical Director of Health Directions in West Columbia, South Carolina was involved with the original landmark study on the reverse aging benefits of growth hormone reported by Cass Terry MD, Ph.D and Dr. Rudman in 1986.  Although he didn't get credit for his involvement with the study, he was in charge of supervision of the clinical trials on many of the participants seen by Dr. L. Cass Terry.  Dr. Shortt, skeptical about the possibility that HGH could be absorbed orally, devised his own in office study of the product formulated by the team of scientists.  The study results, completed May 6, 1999 on six patients, monitored and tested each person for six weeks using the oral spray, three times a day, held under the tongue for two minutes.  Dr. Shortt used a highly respected reference lab to test the blood before and after use of the oral GH with polymer matrix. 

     The oral spray utilized a patented, polymer matrix to encapsulate the large 191 amino acid HGH molecule.  Dr. Shortt knew that people needed HGH to slow and reverse the signs of aging, however he stated that injections removed its wide scale use because of cost and the discomfort of the needle.  He had tested several of the oral HGH products provided by various companies looking for a replacement for injectable HGH.  In May of 1999, Dr. Shortt confirmed to Dr. Delgado that the oral spray demonstrated a significant increase in IGF-1 levels according to before after blood test results.  Furthermore, he said the patients experienced an enhanced feeling of well being, slept better, and reduced body fat.